Tretinoin (Tretineb 0.05%) 0.05% Cream is a derivative of vitamin A, which is used to treat all forms of acne on the face and other parts of the body, from dark spots to pimples. It also tends to smooth out rough skin and reduces the wrinkles and lines associated with age. Each cream contains 0.05% w/v Isotretinoin as its active ingredient.
Drug = Tretinoin
Strength = 0.05%
How to use
Tretinoin comes as a gel, foam, and a cream to apply to the skin.
It is usually applied twice a day, in the morning and the evening.
To help you remember to use Tretinoin, use it at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
Use Tretinoin precisely as directed. Do not use more or less of it or use it more often than prescribed by your doctor.
Dosage of Tretinoin (Tretineb 0.05%) 0.05% Cream
Mottled hyperpigmentation, roughness and fine wrinkling of photodamaged skin:
Adult: As 0.02 or 0.05% cream: Apply a pea-sized amount onto the entire face once daily at night. A therapeutic response may be seen after six months.
Acne vulgaris:
Adult: As 0.01-0.1% cream/gel/alcoholic soln: Apply once or twice a day, usually at bedtime, onto the affected area which has been previously cleansed to remove excessive oiliness and dried. A therapeutic response may be seen after 6-8 weeks.
Missed Dose of Tretinoin (Tretineb 0.05%) 0.05% Cream
Just apply the missed dose and then continue with the regular dosing schedule.
Do not double the dose under any circumstances.
Overdose of Tretinoin (Tretineb 0.05%) 0.05% Cream
If you think you may have used Tretinoin more than the usual dose, please seek medical help immediately.
Contraindications
People with the following medical conditions should not take Tretinoin:
- Pregnancy (first trimester)
- Lactation
Side Effects of Tretinoin (Tretineb 0.05%) 0.05% Cream
Tretinoin may have the following side effects:
- Skin irritation
- Stinging
- Warmth
- Erythema
- Dryness
- Pruritus
- Peeling
- Blistering
- Crusting
- Discomfort
- Temporary hypopigmentation and hyperpigmentation (rare)
- Edema
- Atrophy
- Photosensitivity
Warnings
Do not take Tretinoin with the following medicines:
- Headache
- Nausea
- Vomiting
- Mucocutaneous symptoms
- Transient headache
- Facial flushing
- Cheilosis
- Abdominal pain
- Dizziness
- Ataxia
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicine, supplements and medicines that you buy without a prescription.
This list does not include all medicines that may interact with Tretinoin.
How Does It Work?
Tretinoin works by stimulating the rapid division of cells and skin cell growth, causing the skin’s uppermost layer to slough or exfoliate. This causes deeply rooted comedones (pimples, whiteheads and blackheads) to resurface and prevents the creation of new comedones.
Uses
Tretinoin is used to treat the following conditions:
- Mottled hyperpigmentation
- Roughness and fine wrinkling of photodamaged skin
- Acne vulgaris
Special Precautions and Connected Warnings
Take special precautions if you have the following conditions:
- Eczema
- Sunburn
- History of skin cancer
- Depilation
- Chemical hair treatment and peels
- Dermabrasion or laser resurfacing
- Renal or hepatic impairment
- Children
- Pregnancy
Storage Conditions
- Store between 15-30°C and protected from light.
- Store in a cool, dry place away from the reach of children.
- Do not use Tretinoin that is expired or out of date.
