Exemestane (Aromasin – Xtane) 25mg Tablet – 30 tablets

$96.10

Exemestane (Aromasin – Xtane) 25mg Tablet is an oral steroidal aromatase inhibitor used to treat breast cancer in women who have reached menopause or menstrual cycle has stopped.

Aromatase is an enzyme that converts hormones to estrogen in the body’s adrenal glands. The aromatase inhibitors (AIs) are drugs that reduce estrogen levels by blocking the action of aromatase in the adrenal glands.

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Exemestane (Aromasin – Xtane) 25mg Tablet is an oral steroidal aromatase inhibitor used to treat breast cancer in women who have reached menopause or menstrual cycle has stopped.

Aromatase is an enzyme 25mg Tablet that converts hormones to estrogen in the body’s adrenal glands. The aromatase inhibitors (AIs) are drugs that reduce estrogen levels by blocking the action of aromatase in the adrenal glands.

Drug = Exemestane

Strength = 25mg

Manufacturer = Natco

Quantity per sleeve = 30 Tabs (for the price quoted)

How To Take Exemestane (Aromasin – Xtane) 25mg Tablet

Take it together with food or immediately after a meal. Try to take it at the same time each day.

Exemestane must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed by the doctor.

Take Exemestane exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Dosage of Exemestane (Aromasin – Xtane) 25mg Tablet

Adjuvant therapy for postmenopausal women with hormone receptor positive early breast cancer: 25 mg once daily for 5 years of combined adjuvant hormonal therapy (following tamoxifen). 

Advanced breast cancer in postmenopausal women: 25 mg once daily until evident tumor progression.

Missed Dose of Exemestane (Aromasin – Xtane) 25mg Tablet

If you often forget to take your medicine, let your doctor and pharmacist know.

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your usual dosing schedule.

Do not double a dose under any circumstances.

Overdose

If you think you may have used Exemestane more than the usual dose, please seek medical help immediately.

Contraindications of Exemestane (Aromasin – Xtane) 25mg Tablet

People with the following medical conditions should not take Exemestane:

  • Premenopausal women
  • Pregnancy
  • Lactation

Side Effects of Exemestane (Aromasin – Xtane) 25mg Tablet

Exemestane may have the following side effects:

  • Depression
  • Insomnia
  • Headache
  • Dizziness
  • Hot flushes
  • Abdominal pain
  • Nausea
  • Increased hepatic enzyme, blood bilirubin and blood alkaline phosphatase
  • Increased sweating
  • Joint and musculoskeletal pain
  • Pain
  • Fatigue
  • Anorexia
  • Carpal tunnel syndrome
  • Vomiting
  • Diarrhea
  • Constipation
  • Dyspepsia
  • Alopecia
  • Rash
  • Fracture
  • Osteoporosis
  • Peripheral edema

Warnings of Exemestane (Aromasin – Xtane) 25mg Tablet

Inform your doctor and pharmacist if you are taking any of these medicines:

  • Phenytoin
  • Carbamazepine
  • Phenobarbital
  • Rifampicin
  • St. John’s wort

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.

This list does not include all medicines that may interact with Exemestane.

How Does It Work?

Exemestane is an irreversible, selective aromatase inhibitor which acts as a false substrate for the enzyme and forms an intermediate that binds to its active site. The inactivation or suicide inhibition will prevent the conversion of androgens to estrogens in peripheral tissues, thereby lowering the circulating estrogens in postmenopausal women with breast cancers where growth is estrogen-dependent.

Uses 

  • Exemestane is used to treat the following conditions:
    • Adjuvant therapy for postmenopausal women with hormone receptor positive early breast cancer 
    • Advanced breast cancer in postmenopausal women

Special Precautions and Connected Warnings

Take special precautions if you have the following conditions:

  • Women with premenopausal endocrine status
  • Osteoporosis
  • Concomitant use with estrogen-containing products. 
  • Women with vitamin D deficiency
  • Avoid alcohol

Storage Conditions

  • Store at temperatures not exceeding 30°C.
  • Store in a cool, dry place away from the reach of children.
  • As this is a cancer medicine, always return any unused or expired tablets to the clinic, hospital or pharmacy for disposal. Do not throw it away in the household waste.
  • Do not use Exemestane that is expired or out of expiry date.

Additional information

Application

Tablet

brands

Aromasin – Xtane Exemestane

Chemical

Exemestane

Packaging

Foil in Box

Strength

25 Mg

Quantity per sleeve

30 Tabs (for the price quoted)